besselj(j, ω) function Search Results


psrnatarget web server  (Unigene)
90
Unigene psrnatarget web server
Psrnatarget Web Server, supplied by Unigene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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psrnatarget web server - by Bioz Stars, 2026-11
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analog discovery 2  (Digilent Inc)
90
Digilent Inc analog discovery 2
Analog Discovery 2, supplied by Digilent Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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commercial kits  (Stanbio Inc)
90
Stanbio Inc commercial kits
Commercial Kits, supplied by Stanbio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
commercial kits - by Bioz Stars, 2026-11
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computerized cognitive assessment tool (ccat)  (CogState Ltd)
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CogState Ltd computerized cognitive assessment tool (ccat)
Computerized Cognitive Assessment Tool (Ccat), supplied by CogState Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ws_alloc  (Alloc Modulo LTD)
90
Alloc Modulo LTD ws_alloc
Ws Alloc, supplied by Alloc Modulo LTD, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
ws_alloc - by Bioz Stars, 2026-11
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logistic function (boltzmann function)  (OriginLab corp)
90
OriginLab corp logistic function (boltzmann function)
Logistic Function (Boltzmann Function), supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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heartware lvad  (HeartWare)
90
HeartWare heartware lvad
Heartware Lvad, supplied by HeartWare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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glm function  (RStudio)
90
RStudio glm function
Glm Function, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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digital imaging system visualsonics vevo 2100  (FUJIFILM VisualSonics Inc)
90
FUJIFILM VisualSonics Inc digital imaging system visualsonics vevo 2100
Digital Imaging System Visualsonics Vevo 2100, supplied by FUJIFILM VisualSonics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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emmeans function  (RStudio)
90
RStudio emmeans function
Emmeans Function, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mimetics m2  (Mimetics)
90
Mimetics mimetics m2
(A) Atomic representation of the model of the complex between IL-10 (gray, PDB ID 1J7V) and the helical scaffold used in the rationale for the design of IL-10R1 mimetics (green, N -terminal <t>functionalization</t> in yellow). For clarity, no side chains shown for IL-10 Q38 and IL-10 L48 . (B) Snapshot of complex IL-10/M1 (at 2.9 ns from 10 ns MD simulation). (C) Snapshot of complex IL-10/M4 (at 10 ns). (D) Snapshot of complex IL-10/M6 (at 3.6 ns). Residues involved in recognition are shown in sticks and colored by atom type (IL-10 highlighted in violet in A). Red spheres represent interfacial structural waters observed during MD simulations. Intermolecular H-bonds are depicted by black dashed lines. Figure generated in PyMOL .
Mimetics M2, supplied by Mimetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dmol3 package  (Accelrys)
90
Accelrys dmol3 package
(A) Atomic representation of the model of the complex between IL-10 (gray, PDB ID 1J7V) and the helical scaffold used in the rationale for the design of IL-10R1 mimetics (green, N -terminal <t>functionalization</t> in yellow). For clarity, no side chains shown for IL-10 Q38 and IL-10 L48 . (B) Snapshot of complex IL-10/M1 (at 2.9 ns from 10 ns MD simulation). (C) Snapshot of complex IL-10/M4 (at 10 ns). (D) Snapshot of complex IL-10/M6 (at 3.6 ns). Residues involved in recognition are shown in sticks and colored by atom type (IL-10 highlighted in violet in A). Red spheres represent interfacial structural waters observed during MD simulations. Intermolecular H-bonds are depicted by black dashed lines. Figure generated in PyMOL .
Dmol3 Package, supplied by Accelrys, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) Atomic representation of the model of the complex between IL-10 (gray, PDB ID 1J7V) and the helical scaffold used in the rationale for the design of IL-10R1 mimetics (green, N -terminal functionalization in yellow). For clarity, no side chains shown for IL-10 Q38 and IL-10 L48 . (B) Snapshot of complex IL-10/M1 (at 2.9 ns from 10 ns MD simulation). (C) Snapshot of complex IL-10/M4 (at 10 ns). (D) Snapshot of complex IL-10/M6 (at 3.6 ns). Residues involved in recognition are shown in sticks and colored by atom type (IL-10 highlighted in violet in A). Red spheres represent interfacial structural waters observed during MD simulations. Intermolecular H-bonds are depicted by black dashed lines. Figure generated in PyMOL .

Journal: PLoS ONE

Article Title: Rational Structure-Based Rescaffolding Approach to De Novo Design of Interleukin 10 (IL-10) Receptor-1 Mimetics

doi: 10.1371/journal.pone.0154046

Figure Lengend Snippet: (A) Atomic representation of the model of the complex between IL-10 (gray, PDB ID 1J7V) and the helical scaffold used in the rationale for the design of IL-10R1 mimetics (green, N -terminal functionalization in yellow). For clarity, no side chains shown for IL-10 Q38 and IL-10 L48 . (B) Snapshot of complex IL-10/M1 (at 2.9 ns from 10 ns MD simulation). (C) Snapshot of complex IL-10/M4 (at 10 ns). (D) Snapshot of complex IL-10/M6 (at 3.6 ns). Residues involved in recognition are shown in sticks and colored by atom type (IL-10 highlighted in violet in A). Red spheres represent interfacial structural waters observed during MD simulations. Intermolecular H-bonds are depicted by black dashed lines. Figure generated in PyMOL .

Article Snippet: Thus, based on the structure of the refined model of the M1 /IL-10 complex ( ) and taking into account the interaction energies obtained with the sp 3 and sp 2 amine cation chemical probes ( vide supra ), two new mimetics ( M2 , M3 ; differing in tryptophan vs . its 5-hydroxy derivative in position 2) were designed by N-terminal functionalization with 4-guanidinobutanoyl, providing a positively charged H-bond donor for potential interaction with the negatively charged side chain of IL-10 E50 (helix B).

Techniques: Generated